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Expertise

Topical and transdermal products

The clinical development strategies for topical and transdermal products such as cremes, ointments, gels, spays, eye-drops or topically applied Transdermal Delivery Systems (TDDS) and patches require regulatory pathways that are often different from solid forms. CCDRD AG has already performed numerous clinical studies for topical products and TDDS and is able to align a complete clinical registration package for such products.

Study types offered:

  • Therapeutic equivalence trials
  • Pharmacokinetic trials with topical or transdermal products
  • Adhesions studies
  • Skin irritation and senzitization studies
  • Trials with Transdermal delivery systems (TDDS)

Experience with topical and TDDS products

Aciclovir creme

Phase III therapeutic equivalence trials

Betamethasone creme

Phase III therapeutic equivalence trials

Buprenorphine TDDS

  • Pharmacokinetic trials
  • Adhesion study
  • Skin irritation assessment

Calcipotriol/Betamethasone ointment

Phase III therapeutic equivalence trials

Clotrimazol creme

Phase III therapeutic equivalence trials

Diltiazem paste

Pharmacokinetic trial

Estradiol gel

Pharmacokinetic trials

Latanoprost eye drops

Phase III therapeutic equivalence trials

Mometasone nasal spray

Pharmacokinetic trials

Sulfadiazine creme

Phase III therapeutic equivalence trials

Terbinafine creme

Phase III therapeutic equivalence trials

Timolol eye drops

Phase III therapeutic equivalence trials

Triamcinolone acetonide creme

Skin irritation study

Tetryzoline eye drops

Pharmacodynamic equivalence trial

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